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STI Prevention Vaccines



Using condoms is key to preventing STIs. For high-risk individuals, there are vaccines and medication available at the clinic that help to prevent STIs.

Who are the vaccines for?

These vaccines are available for gay, bisexual, or men who have sex with men that are at a higher risk and if they:

  • Have sex with multiple partners.
  • Have group sex.
  • Have had a bacterial STI in the last 12 months.
  • Find it difficult to use condoms every time.
  • Have had sex with someone with an STI.

These vaccines may also be available to you if you don’t fit the above criteria but are high-risk. Clinicians will assess whether you are eligible at an appointment.

Please note: We are unable to provide vaccines for travel purposes -please see your GP.

How do I access these vaccines?

If you’re eligible and have visited the clinic for PrEP, you may receive a text inviting you to book an appointment for these vaccines.

You can also ask about these vaccines at your routine PrEP appointment or you can phone the clinic to find out of you’re eligible.

What vaccines are available?

MenB vaccine (gonorrhoea)

The Meningocococcal B (MenB) vaccine, also called Bexsero, is available for eligible individuals from September 2025. It gives a 30-40% protection against gonorrhoea. It requires two injections at least four weeks apart.


Mpox vaccine

Mpox (previously known as monkeypox), can be transmitted through sexual contact. The Mpox vaccine provides good protection against the mpox virus. It’s usually given as two injections at least 28 days apart.


Hep A vaccine

Two injections given 6-12 months apart to protect against Hepatitis A.


Hep B vaccine

Three injections to protect against Hepatitis B. Usually, the second injection is given one month after the first, and the final injection is given 6 months after the first.


HPV vaccine

Two injections taken at least six months apart. (Sometimes three vaccines are needed.) This vaccine is available for gay, bisexual, and other men who have sex with men who are up to, and including, 45 years of age.


Prevention medication

Alongside vaccines, if you visit the clinic and are high-risk, clinicians may offer you prevention medication. This includes:

  • PrEP (a pill you can take before sex that offers near complete protection from HIV).
  • PEP (a pill you take if you think you may have been exposed to HIV within the last 72 hours which may stop you becoming infected.)
  • DoxyPEP (a pill you take after sex to prevent syphilis).

Learn more about prevention medication